BioCore's Technology
The wound healing properties of collagen are attributed to its unique structure. For example:
- Collagen must be in the form of ordered structure to interact with platelets to stop bleeding (Brass and Bensusan, 1974; Jaffe and Dykin, 1974)
- Structure of collagen is important for chemotactic attraction of monocytes as native collagen is 10 times more potent than denatured collagen chains (Postlewaithe and Kang, 1976).
- The collagen in fibrillar form is preferred by cells because of the unique properties of collagen fibrils (Reddi, 1976).
- Intact collagen has specific binding sites for cells (Kleinman et al., 1976)
- Both the helical and the non-helical regions in a collagen molecule are essential for biological response (Reddi, 1976)
The structure of collagen is very important for wound healing benefits. BioCore’s technology keeps the structure of collagen intact at all levels. Figures 1-3 show BioCore’s products having collagen’s defined structure at all levels. As a comparison, a text book picture of bovine collagen is in Fig. 4. Such structures are absent in some of the other collagen products available in the market (figures 5-7)
